What is Nicotinamide Riboside?

Nicotinamide riboside (NR) is a water-soluble variant of vitamin B3. It is a form of niacin that can be converted into nicotinamide adenine dinucleotide (NAD+), an important molecule involved in various biological processes in our body. This substance is found in food sources such as milk, brewer's yeast and certain vegetables, but in limited quantities. In addition, nicotinamide riboside can be produced by specific bacteria and yeasts. It is often taken as a supplement, sometimes together with NMN supplements, as an alternative or for variation

Benefits of Nicotinamide Riboside

Nicotinamide riboside (NR), often referred to as the vitamin for healthy aging, is a new form of vitamin B3 that may improve the way we age. It is important to understand that the real causes of aging lie deep within our cells. As we age, we may experience a variety of changes, including aching joints, tired muscles, and changes in sleeping and eating habits. Taking an NR supplement may help provide the following benefits:

• Supports the regenerative capacity of the skin
• Contributes to normal mental performance and psychological functioning
• Helps maintain normal structure and function of mucous membranes
• Has a beneficial effect on reducing fatigue
• Contributes to normal energy-yielding metabolism
• Has a positive effect on the functioning of the nervous system

Information about Nicotinamide Riboside Benefits and European Legislation

Skins Unlimited is subject to European legislation, which means we are unable to provide extensive information on the applications and possible health benefits of the supplement Nicotinamide Riboside (NR). Since we offer this product online, there are restrictions on the information we are allowed to provide. For detailed information, we recommend consulting scientific studies via platforms such as Pubmed or independent orthomolecular websites. These sources can mention the benefits of Nicotinamide Riboside, as they have no commercial interest.

Differences between NR supplement, vitamin B3 and NAD+

Nicotinamide adenine dinucleotide (NAD+) and vitamin B3 (niacin) are both essential for energy metabolism in our body.

NAD+ functions as a coenzyme necessary for the function of several enzymes involved in energy production in cells. Vitamin B3, or niacin, is a water-soluble vitamin required for the conversion of food into energy. Nicotinamide riboside (NR) is a specific form of vitamin B3 and is used as a dietary supplement.

There are some key differences between these substances. NAD+ is a coenzyme that occurs naturally in our bodies and is involved in various biological processes. Vitamin B3 (niacin), on the other hand, is an essential nutrient that cannot be produced by the body and must be obtained through diet. The main difference between NAD+ and NR is that NAD+ is naturally produced in the body from other compounds, while NR does not occur naturally in the body and can only be taken as a supplement.

Differences between Nicotinamide Riboside (NR) and Nicotinamide (NAM)

Nicotinamide riboside (NR) and nicotinamide (NAM) are both variants of vitamin B3, also known as niacin. The main distinction between NR and NAM lies in their chemical structure and the way they are metabolized by the body. NR is a form of niacin that is converted to nicotinamide adenine dinucleotide (NAD+) in the body. It is considered a precursor to NAD+ because it can be converted to NAD+ through a series of enzymatic reactions. In general, NR is considered a more efficient precursor to NAD+ than NAM because it is less dependent on other metabolic pathways for the production of NAD+

Differences between our NR supplement and Niagen

True Niagen is a brand name for nicotinamide riboside and there is no difference with our NR supplement. The active ingredient is identical and both products are independently tested for purity. However, True Niagen does have additional substances added to the capsules, such as microcrystalline cellulose (a filler), hydroxypropyl methylcellulose and an anti-caking agent. In addition, you pay a higher price with Niagen because of the marketing they use for their product. If you are looking for the purest nicotinamide riboside, then you have come to the right place.

How do you use Nicotinamide Riboside supplement?

• The minimum recommended dosage is approximately 400 mg up to a maximum of 1 gram (1000 mg)
• Preferably take it in the morning, together with a meal.
• The powder can be mixed with water or through food.
• Store the product at a stable temperature, but we recommend keeping it refrigerated after opening. For longer storage, you can place it in the freezer.
• Comes with a free measuring spoon that contains 0,4g and is dishwasher safe.
• For accurate dosing it is recommended to use a precision balance to use.
• Consult a specialist before taking Nicotinamide Riboside if you are ill, taking medication, are pregnant or breastfeeding.
• Remember that a healthy lifestyle and a varied, balanced diet are important; Nicotinamide Riboside is not a substitute for these.

Nicotinamide Riboside Side Effects

Nicotinamide riboside is considered safe with no side effects

Safety was investigated in a study published in Scientific Reports. Researchers found that administering NR in doses of 100, 300, and 1.000 milligrams over an eight-week, randomized, double-blind, placebo-controlled clinical trial caused no adverse effects. In other human studies, taking up to 2.000 milligrams per day was also found to be well-tolerated, with no adverse effects. However, it is wise to consult a doctor before taking higher than the recommended maximum dose of NR.

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